thyroid-stimulating antibodies

thyroid-stimulating antibodies
Long-acting thyroid stimulator is an autoantibody found in many cases of primary thyrotoxicosis which causes hyperplasia of the thyroid by undetermined mechanisms. Human thyroid-stimulating immunoglobulin is a different antibody found in all or nearly all cases of primary thyrotoxicosis and may act by binding to the thyrotropin (TSH) receptor site, causing increased synthesis of thyroglobulin.

Dictionary of molecular biology. 2004.

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  • Thyroid-stimulating hormone — protein Name = Thyroid stimulating hormone, alpha (Glycoprotein hormones, alpha polypeptide) caption = width = HGNCid = 1885 Symbol = CGA AltSymbols = HCG, GPHa, GPHA1 EntrezGene = 1081 OMIM = 118850 RefSeq = NM 000735 UniProt = P01215 PDB =… …   Wikipedia

  • thyroid-stimulating immunoglobulins — (TSI) circulating IgG antibodies with the ability to mimic thyrotropin by binding to receptors for it on thyroid cells and activating adenylate cyclase, thus causing an increase in the level of the intracellular second messenger cyclic AMP, which …   Medical dictionary

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  • thyroid function test — ▪ medicine       any laboratory procedure that assesses the production of the two active thyroid hormones, thyroxine (T4) and triiodothyronine (T3), by the thyroid gland and the production of thyrotropin (thyroid stimulating hormone, TSH), the… …   Universalium

  • Thyroid — Infobox Anatomy Name = Thyroid Latin = glandula thyroidea GraySubject = 272 GrayPage = 1269 Caption = Endocrine system Caption2 = Thyroid and parathyroid. Precursor = 4th Branchial pouch System = endocinal jubachina system Artery = superior… …   Wikipedia

  • Thyroid hormone resistance — MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D018382 Thyroid hormone resistance describes a rare syndrome where the thyroid hormone levels are elevated but the thyroid stimulating hormone (TSH) level is not suppressed, or not… …   Wikipedia

  • endocrine system, human — ▪ anatomy Introduction  group of ductless glands (gland) that regulate body processes by secreting chemical substances called hormones (hormone). Hormones act on nearby tissues or are carried in the bloodstream to act on specific target organs… …   Universalium

  • Diffuse toxic goiter — Graves disease, the most common cause of hyperthyroidism (overactivity of the thyroid gland), with generalized diffuse overactivity ( toxicity ) of the entire thyroid gland which becomes enlarged into a goiter. There are three clinical components …   Medical dictionary

  • Goiter, diffuse toxic — Graves disease, the most common cause of hyperthyroidism (overactivity of the thyroid gland), with generalized diffuse overactivity ( toxicity ) of the entire thyroid gland which becomes enlarged into a goiter. There are three clinical components …   Medical dictionary

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